How to Build a Medicube PDRN Routine: Serum, Cream and Mask in the Right Order

Medicube's PDRN Pink line is a complete routine built around one ingredient: salmon-derived PDRN paired with collagen and peptides. It has three core steps, a daily serum, a daily cream, and a weekly mask, and they are designed to layer in a specific order. Here is how the routine runs.

Step 1: cleanse

Any low-irritation cleanser works. Within the Medicube range, the Zero Foam Cleanser is the natural fit: a soft, low-foam gel that cleans without stripping, which matters when the rest of the routine is built around hydration.

Step 2: PDRN Pink Peptide Serum

The PDRN Pink Peptide Serum is the centre of the routine: 10,000 ppm PDRN, five peptides, and hydrolysed collagen in a lightweight pink serum. Apply two to three drops to damp skin after cleansing, morning and night, and press it in rather than rubbing. New to the ingredient? Our explainer on what PDRN is covers it in two minutes.

Step 3: PDRN Pink Collagen Capsule Cream

The Capsule Cream seals the serum in. It is a rich but comfortable cream with the same PDRN and collagen base, plus niacinamide. Use it as your final skincare step at night, and before sunscreen in the morning. If your skin runs oily, the lighter Collagen Jelly Cream works as the daytime alternative.

Weekly: PDRN Pink Collagen Gel Mask

Once or twice a week, swap the evening serum-and-cream steps for the PDRN Pink Collagen Gel Mask. It is a hydrogel sheet soaked in the same actives, worn for 20 to 30 minutes after cleansing. It is the highest-dose hit of the routine and a good night-before-an-event step.

Shop the routine

Morning vs night

Time	Routine
Morning	Cleanse, PDRN serum, Jelly Cream or Capsule Cream, sunscreen
Night	Cleanse, PDRN serum, Capsule Cream
1-2x weekly	Cleanse, Gel Mask (20-30 min), Capsule Cream

Adding retinol

PDRN layers comfortably with retinoids, and many people run both: retinal at night, PDRN to keep the barrier calm. If that is the plan, our PDRN vs retinol comparison covers the order of operations.

You can find the full line on our Medicube collection page. Questions about fitting PDRN into an existing routine? Email contact@dlux-essentials.com.